Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Jervine

A sonic hedgehog (Shh) pathway inhibitor
Catalog #: 2357

In stock

SKU-Size Size Price Qty
2357-1 1 mg
$125.00
2357-5 5 mg
$485.00
More Sizes Get Quote

Product Details

Alternate Name (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1­1bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexad­ecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H­-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1­H)-one
Appearance White to off-white solid
CAS # 469-59-0
Molecular Formula C₂₇H₃₉NO₃
Molecular Weight 425.6
Purity ≥98% by TLC
Solubility DMSO (5 mg/ml) or EtOH (10 mg/ml)
SMILES CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
InChi InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChi Key CLEXYFLHGFJONT-DNMILWOZSA-N
PubChem CID 10098
MDL Number MFCD01684066
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. Structurally similar to cyclopamine (Cat. No. 1578). Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Tomatidine (Cat. No. 1893) is a useful negative control.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.