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Jarid1b polyclonal antibody

Polyclonal Antibody to detect Jarid 1b in mouse samples.
Catalog #: 6854
$185.00

Product Details

Cat # +Size 6854-50
Size 50 μl
Antibody Target Jarid1b
Alternate Name CT31, PLU1, PUT1, RBBP2H1, RBP2-like
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Polyclonal antibody raised in rabbit against mouse Jarid1b (Jumonji, AT rich interactive domain 1B), using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein.
Accession # Q9UGL1
Gene ID 10765
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Purification Whole Anti-Sera
Species Reactivity Mouse.
Application Western blot, ELISA.
Positive Control Western blot: NIH3T3 and embryonic stem cells, ELISA: Peptides.
Application & Usage Western Blot: 1:500, ELISA: 1:100 – 1:200.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

JARID1b is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1b itself may function as a tumor suppressor.


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