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JAK-STAT Signaling

The JAK/STAT signaling pathway transmits a signal from outside the cell eventually resulting in DNA transcription and activity in the cell. Leptin (a product of the obese gene) can induce a cascade of events through its receptor and the JAK/STAT pathway. Significantly, Leptin mediated signaling through the JAK2/STAT3 pathway affects appetite and has been implicated in various carcinomas. BioVision provides many research grade products for these targets. Check out our interactive pathway.
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