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Ixazomib

A potent proteasome inhibitor
Catalog #: B2384
SKU-Size Size Price Qty
B2384-5 5 mg
$125.00
B2384-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid, MLN2238, MLN-2238
Appearance White solid
CAS # 1072833-77-2
Molecular Formula C₁₄H₁₉BCl₂N₂O₄
Molecular Weight 361.03
Purity ≥98% by HPLC
Solubility >25 mg/ml in DMSO
SMILES B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
InChi InChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
InChi Key MXAYKZJJDUDWDS-LBPRGKRZSA-N
PubChem CID 25183872
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ixazomib (MLN-2238), is a potent proteasome inhibitor (PI) with potential antineoplastic activity. MNL-2238 is a biologically active form of MLN9708. MLN-2238 has an improved pharmacodynamic profile and antitumor activity compared with bortezomib in both OCI-Ly10 and PHTX22L models.


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