Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

IWP-2

An inhibitor of Wnt secretion and processing
Catalog #: 1962
SKU-Size Size Price Qty
1962-5 5 mg
$130.00
1962-25 25 mg
$520.00
More Sizes Get Quote

Product Details

Alternate Name N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Appearance Beige solid
CAS # 686770-61-6
Molecular Formula C₂₂H₁₈N₄O₃S₃
Molecular Weight 466.6
Purity ≥98% by TLC
Solubility DMSO (~5 mg/ml with warming)
SMILES CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4
InChi InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)
InChi Key WRKPZSMRWPJJDH-UHFFFAOYSA-N
PubChem CID 2155128
MDL Number MFCD04457599
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC₅₀ = 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.