ISX9

A neurogenic differentiation inducer
Catalog #: 2563 | abID:

Product Details

Alternate Name N-cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Appearance Beige solid
CAS # 832115-62-5
Molecular Formula C₁₁H₁₀N₂O₂S
Molecular Weight 234.28
Purity ≥98% by TLC
Solubility DMSO (~60 mg/ml) or EtOH (~ 15 mg/ml)
SMILES O=C(NC1CC1)C2=NOC(C3=CC=CS3)=C2
InChi InChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14)
InChi Key SYENTKHGMVKGAQ-UHFFFAOYSA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ISX9 promotes neurogenesis in vivo enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts and enhances memory. Induces robust neuronal differentiation in adult neural stem cells. Increases insulin production by pancreatic β cells. Blocks malignant astrocyte proliferation, downregulates their astrocyte character, induces reentry into the cell cycle and upregulates neuronal gene expression.


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