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Isopeptidase T (short form), human recombinant

A ubiquitin-specific processing protease
Catalog #: 4861

Product Details

Cat # +Size 4861-25
Size 25 μg
Alternate Name USP5; Ubiquitin-specific protease 5
Gene Symbol UBP5
Gene ID 8078
Accession # P45974
Source E. coli
Appearance Liquid
Physical Form Description Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 mM β-mercaptoethanol, pH 7.5.
Molecular Weight 93.4 kDa
Purity by SDS-PAGE ≥95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans


Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the UBPs hydrolyze isopeptide bonds between ubiquitin and the substrate protein or within polyubiquitin chains. Human isopeptidase T (isoT) is an UBP capable of binding ubiquitin that specifically disassembles free polyubiquitin chains linked through isopeptide bonds involving the K48 of ubiquitin into ubiquitin monomers.

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