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Isopeptidase T (long form), human recombinant

A ubiquitin-specific processing protease
Catalog #: 4862

Product Details

Cat # +Size 4862-25
Size 25 μg
Alternate Name USP5; Ubiquitin-specific protease 5
Gene Symbol UBP5
Gene ID 8078
Accession # P45974
Source E. coli
Appearance Liquid
Physical Form Description Supplied at a concentration of 0.4 mg/ml in 50 mM Tris, 10 Mmn β-mercaptoethanol, pH 7.5.
Molecular Weight 97.0 kDa
Purity by SDS-PAGE ≥95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans


Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.

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