IRF3, human recombinant

Plays a crucial role in activation of innate immunity and inflammation in response to viral infection
Catalog #: 7323 | abID:

Product Details

Cat # +Size 7323-50
Size 50 μg
Alternate Name Interferon regulatory factor-3
Gene Symbol IRF3
Gene ID 3661
Accession # Q14653
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in Phosphate-buffered saline (pH 7.4).
Molecular Weight 13 kDa (112 aa, 1-112 aa), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALNRKEGL RLAEDRSKDP HDPHKIYEFV NS
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. Recombinant human IRF3 was expressed in E.coli and purified by using conventional chromatography techniques.


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