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IRF2, human recombinant

Competitively inhibits the IRF1-mediated transcriptional activation
Catalog #: 7322
$375.00

Product Details

Cat # +Size 7322-100
Size 100 μg
Alternate Name Interferon regulatory factor-2
Gene Symbol IRF2
Gene ID 3660
Accession # P14316
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT and 10% glycerol.
Molecular Weight 15 kDa (133 aa, 1-113 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Recombinant human IRF2 was expressed in E.coli and purified by using conventional chromatography techniques.


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