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IRF1, human recombinant

A transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes
Catalog #: 7321
$295.00

Product Details

Cat # +Size 7321-100
Size 100 μg
Alternate Name Interferon regulatory factor-1, MAR
Gene Symbol IRF1
Gene ID 3659
Accession # P10914
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Molecular Weight 15 kDa (134 aa, 1-114 aa + His tag), confirmed by MALDI-TOF.
Purity by SDS-PAGE ≥90%
Endotoxin Level < 1.0 EU per 1 microgram of protein
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E.coli and purified by using conventional chromatography techniques.


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