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An inhibitor of CK2
Catalog #: B2939
SKU-Size Size Price Qty
B2939-5 5 mg
B2939-25 25 mg
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Product Details

Alternate Name 5,6-Dihydro-5-oxo-indolo[1,2-a]quinazoline-7-acetic acid; 2-(5-Oxo-7H-indolo[1,2-a]quinazolin-7-yl)acetic acid; Casein Kinase II Inhibitor IX; CGP029482
Appearance Solid
CAS # 391670-48-7
Molecular Formula C₁₇H₁₂N₂O₃
Molecular Weight 292.29
Purity 95%
Solubility 10 mg/ml in DMSO
InChi InChI=1S/C17H12N2O3/c20-15(21)9-12-10-5-1-3-7-13(10)19-14-8-4-2-6-11(14)17(22)18-16(12)19/h1-8,12H,9H2,(H,20,21)
PubChem CID 76844772
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


IQA is an indoloquinazoline derivative that acts as a selective and reversible casein kinase (CK2) inhibitor with an IC₅₀ of 390 nM with 100 µM ATP. It inhibits CK2 in an ATP- and GTP-competitive manner (Ki is 0.17 and 0.21 µM, respectively). It induces apoptosis in different tumor derived cell lines.

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