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IQ-1

A stem cell differentiating agent
Catalog #: 1663
$142.00

Product Details

Cat # +Size 1663-1
Size 1 mg
Alternate Name 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
Appearance Orange solid
CAS # 331001-62-8
Molecular Formula C₂₁H₂₂N₄O₂
Molecular Weight 362.42
Purity ≥95% by HPLC
Solubility DMSO
SMILES CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
InChi InChI=1S/C21H24N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,18-19,23H,12H2,1-3H3,(H2,22,27)
InChi Key WQFHCZGUBRVAAW-UHFFFAOYSA-N
PubChem CID 11152734
MDL Number MFCD00354369
Handling Protect from air and light
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.


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