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Ipragliflozin

A potent sodium-glucose cotransporter 2 (SGLT2) inhibitor
Catalog #: B1926
SKU-Size Size Price Qty
B1926-5 5 mg
$95.00
B1926-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name (2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Appearance White to off-white solid
CAS # 761423-87-4 
Molecular Formula C₂₁H₂₁FO₅S 
Molecular Weight 404.45
Purity ≥98% by HPLC
Solubility DMSO (~30 mg/ml)
SMILES C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
InChi InChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1
InChi Key AHFWIQIYAXSLBA-RQXATKFSSA-N
PubChem CID 10453870
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ipragliflozin is a potent inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC₅₀ = 7.4 nM for human SGLT2 in vitro) that increases excretion of glucose.Iipragliflozin is found to promote preferential loss of fat mass in a rat model of non-obese type 2 diabetes mellitus (T2DM).


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