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A potent and selective PI3Kγ Inhibitor
Catalog #: B1971
SKU-Size Size Price Qty
B1971-5 5 mg
B1971-25 25 mg
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Product Details

Alternate Name 2-amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Appearance Crystalline solid
CAS # 1693758-51-8
Molecular Formula C₃₀H₂₄N₈O₂
Molecular Weight 528.56
Purity ≥98% by HPLC
Solubility DMSO (~15 mg/ml)
InChi InChI=1S/C30H24N8O2/c1-19(34-29(39)26-27(31)35-37-15-7-14-32-28(26)37)24-16-22-9-6-8-21(13-12-20-17-33-36(2)18-20)25(22)30(40)38(24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3,(H2,31,35)(H,34,39)
PubChem CID 118004470
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


IPI-549 is a potent and selective PI3Kγ Inhibitor (IC₅₀ of 16 nM). It displays no significant inhibition for a panel of 468 mutant and non-mutant protein and lipid kinases (including Class II PI3K isoforms) at 1 µM.

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