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Ionomycin (Calcium salt)

A calcium ionophore
Catalog #: 1566
SKU-Size Size Price Qty
1566-1 1 mg
$115.00
1566-5 5 mg
$405.00
More Sizes Get Quote

Product Details

Appearance White to off-white solid
CAS # 56092-82-1
Molecular Formula C₄₁H₇₀O₉.Ca²⁺
Molecular Weight 747.1
Purity ≥99%
Solubility DMSO
SMILES CC(CCC(=O)[O-])CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)[O-].[Ca+2]
InChi InChI=1S/C41H72O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47);/q;+2/p-2/b13-11+,34-24-;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1
InChi Key WKRWUYKLUMMAKG-WYGBAUISSA-L
PubChem CID 6446270
MDL Number MFCD00083634
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons. More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.


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