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Interactive Pathways

A biological pathway is a series of actions with in molecules in a cell leading towards generation of certain product or a change in a cell. These actions in a cell can trigger the formation of new molecules, such as a fat or protein or the genes get turned on and off or spur a cell to move. BioVision’s assay kits can be used in various cellular pathway studies. Below are the different pathway diagrams with our kits numbers wherever applicable.


Pathway

Description

Glyoxalase Pathway

The Glyoxalase cyclic pathway, consists of two enzymes (Glyoxalase I and Glyoxalase II), is responsible for the detoxification against molecules involved in the glycation of proteins and DNA, such as Methylglyoxal and reactive aldehyde molecules. BioVision is thrilled to be the first company offering a complete set of assay kits dedicated for the study of the components of the Glyoxalase System.

Immune CheckPoints Signaling

Immune CheckPoints consists of vast number of inhibitory pathways embedded into the immune system that are crucial in enabling self-tolerance and restraining collateral tissue damage during immune response against microbial attack. Here is an interactive Immune checkpoint pathway for BioVision’s products for CTLA4, PD-1, PD-L1, PI3K and many more.

JAK-STAT Signaling

The JAK/STAT signaling pathway transmits a signal from outside the cell eventually resulting in DNA transcription and activity in the cell. Leptin (a product of the obese gene) can induce a cascade of events through its receptor and the JAK/STAT pathway. Significantly, Leptin mediated signaling through the JAK2/STAT3 pathway affects appetite and has been implicated in various carcinomas. BioVision provides many research grade products for these targets. Check out our interactive pathway.

Creatinine Biosynthesis

Creatinine, a natural waste, is produced during muscle metabolism or digestion of meat. Creatinine levels indicate proper kidney function: higher concentrations in blood are indicators of kidney damage due diabetes or kidney disease complications. BioVision offers the most complete series of assays measuring various metabolites, cofactors, and enzymes involved in the synthesis of Creatinine.

EGFR Signaling

Epidermal growth factor receptor (EGFR) is a transmembrane protein that is activated by binding of its specific ligands. EGFR is crucial for ductal development of the mammary glands and plays important role in cancer, inflammatory diseases, monogenic diseases. Hence very useful target for many of the above mentioned diseases.

Hedgehog Signaling

The Hedgehog signaling pathway plays important role in cell differentiation by transmitting the information to embryonic cells. Concentration of various hedgehog signaling proteins differs in various parts of embryo; any malfunction of this pathway may lead to basal cell carcinoma in adults. BioVision provides many products for various targets in hedgehog signaling pathway.

Glycolysis

Glycolysis is a metabolic pathway converting glucose into pyruvate, the high energy released is utilized in the formation of ATP and NADH molecules. BioVision provides various metabolite, enzymes and co-enzyme to assay kits to expedite your research.

Kreb’s Cycle / Citric Acid Cycle/ Tricarboxylic Acid Cycle

This pathway involves many biochemical reactions used by all aerobic organisms to release stored energy through oxidation of acetyl-CoA derived carbohydrates, fats and proteins into carbon dioxide and ATP. BioVision provides assay kits to measure various metabolites, co-enzymes and enzymes for your research.

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