Ingenol-3-angelate, PKC activator (ab144280)
Key features and details
- Specific protein kinase C (PKC) activator.
- CAS Number: 75567-37-2
- Purity: > 98%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ingenol-3-angelate, PKC activator -
Description
Specific protein kinase C (PKC) activator. -
Alternative names
- PEP 005
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Purity
> 98% -
CAS Number
75567-37-2 -
Chemical structure
Properties
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Chemical name
(2Z)-2-Methyl-2-butenoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester -
Molecular weight
430.53 -
Molecular formula
C25H34O6 -
PubChem identifier
6918670 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C/C=C(/C)\C(=O)O[C@H]1C(=C[C@@]23[C@@]1([C@@H](C(=C[C@H](C2=O)[C@H]4[C@H](C4(C)C)C[C@H]3C)CO)O)O)C -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab144280 has been referenced in 1 publication.
- De Virgiliis F et al. Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling. Nat Commun 11:6425 (2020). PubMed: 33349630