Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

INCB057643

A potent and selective BET inhibitor
Catalog #: B2438

In stock

SKU-Size Size Price Qty
B2438-1 1 mg
$85.00
B2438-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Appearance Crystalline solid
CAS # 1820889-23-3
Molecular Formula C₂₀H₂₁N₃O₅S
Molecular Weight 415.46
Purity ≥98% by HPLC
Solubility >50 mg/ml in DMSO
SMILES CC1(C(=O)N(C2=C(O1)C(=CC(=C2)S(=O)(=O)C)C3=CN(C(=O)C4=C3C=CN4)C)C)C
InChi InChI=1S/C20H21N3O5S/c1-20(2)19(25)23(4)15-9-11(29(5,26)27)8-13(17(15)28-20)14-10-22(3)18(24) 16-12(14)6-7-21-16/h6-10,21H,1-5H3
InChi Key VZSAMEOETVNDQH-UHFFFAOYSA-N
PubChem CID 118467751
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

INCB057643 is a potent and selective BET inhibitor; displays more effectivity against androgen-dependent (VCaP and LNCaP) than androgen-independent (DU145 and PC3) cells with IC50 of <100 nM and >500 nM, respectively; significantly causes inhibition of tumor growth in mice bearing 22Rv1 tumor xenografts. INCB057643 inhibits proliferation of prostate cancer cell lines.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.