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Inauhzin

A potent SIRT inhibitor
Catalog #: 9555
SKU-Size Size Price Qty
9555-5 5 mg
$195.00
9555-25 25 mg
$795.00
More Sizes Get Quote

Product Details

Alternate Name 2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one
Appearance White solid
CAS # 309271-94-1
Molecular Formula C₂₅H₁₉N₅OS₂
Molecular Weight 469.58
Purity ≥98% by HPLC
Solubility DMSO (~5 mg/ml)
SMILES CCC(C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31)SC4=NC5=C(C6=CC=CC=C6N5)N=N4
InChi InChI=1S/C25H19N5OS2/c1-2-19(33-25-27-23-22(28-29-25)15-9-3-4-10-16(15)26-23)24(31)30-17-11-5-7-13-20(17)32-21-14-8-6-12-18(21)30/h3-14,19H,2H2,1H3,(H,26,27,29)
InChi Key VHUOXERIKQWIJE-UHFFFAOYSA-N
PubChem CID 5494506
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Inauhzin is a potent SIRT inhibitor that effectively reactivates p53 by inhibiting SIRT1 activity. Inauhzin inhibits cell proliferation, induces senescence, and p53-dependent apoptosis of human cancer cells without apparent toxicity to normal cells.


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