A Toll-like receptor 7 (TLR-7) agonist
Catalog #: 1698 | abID: ab141410

Product Details

abID ab141410
Alternate Name 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837
Appearance White to off-white solid
CAS # 99011-02-6
Molecular Formula C₁₄H₁₆N₄
Molecular Weight 240.3
Purity ≥95% by HPLC
Solubility DMSO
InChi InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
PubChem CID 57469
MDL Number MFCD00866946
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway.

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