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Imidapril hydrochloride

A potent angiotensin converting-Enzyme (ACE) inhibitor
Catalog #: B2135

In stock

SKU-Size Size Price Qty
B2135-5 5 mg
$85.00
B2135-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride, Novaloc, TA 6366, Tanapril
Appearance White to off-white solid
CAS # 89396-94-1
Molecular Formula C₂₀H₂₇N₃O₆ · HCl
Molecular Weight 441.91
Purity ≥98% by HPLC
Solubility H₂O (>5 mg/ml)
SMILES CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C2=O)C)C(=O)
InChi InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
InChi Key LSLQGMMMRMDXHN-GEUPQXMHSA-N
PubChem CID 5485193
MDL Number MFCD00923828
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Imidapril is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme (ACE) inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC₅₀ = 2.6 nM), thereby preventing vasoconstriction and decreasing aldosterone secretion by the adrenal cortex which leads to an increase in sodium excretion and subsequently increases water outflow.


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