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IL-8 (77 a.a.), human recombinant

based on 1 citations in multiple journalsIL-8 (77 a.a.), human recombinant14.1 4
A neutrophil chemotactic factor
Catalog #: 4149

In stock

SKU-Size Size Price Qty
4149-25 25 μg
$215.00
4149-1000 1 mg
$3,600.00
More Sizes Get Quote

Product Details

Alternate Name IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctaki
Gene Symbol IL8
Gene ID 3576
Accession # P10145
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 8.9 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25 to 150 ng/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

IL-8 is a proinflammatory CXC chemokine that can signmal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant IL-8 (endothelial-derived) is a 8.9 kDa protein containing 77 amino acid residues.


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Reeves, E. P. et. al. Nebulized Hypertonic Saline Decreases IL-8 in Sputum of Patients with Cystic Fibrosis. Am. J. Respir. Crit. Care Med., Jun 2011; 183: 1517 - 1523.
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