IL-7, human recombinant

A cytokine important for B and T cell development
Catalog #: 4146 | abID:

Product Details

Alternate Name IL-7, Interleukin-7
Gene Symbol IL7
Gene ID 3574
Accession # P13232
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from a concentrated solution in water containing 1X PBS pH 7.4
Molecular Weight 17.4 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is <0.5 ng/ml, corresponding to a specific activity of >2 x 10⁶ units/mg.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1 mg/ml, pipet up-and-down to dissolve. The solution can be diluted into other buffered solutions or stored at –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.

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Staron, M. et al. gp96, an Endoplasmic Reticulum Master Chaperone for Integrins and Toll-Like Receptors, Selectively Regulates Early T and B Lymphopoiesis. Blood 2010 115: 2380-2390.
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