IL-6, rat recombinant

An important mediator of acute phase response
Catalog #: 4145 | abID: ab285522

Product Details

abID ab285522
Alternate Name IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2, IL-6, Interleukin HP-1, B-cell hybridoma growth factor, B-cell stimulatory factor 2, CTL differentiation factor, Interferon beta-2.
Gene Symbol IL6
Gene ID 24498
Accession # P20607
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives.
Molecular Weight 21.7 kDa
Purity by SDS-PAGE ≥90%
Purity by ≥90%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is <0.01 ng/ml, corresponding to a specific activity of ≥1 x 10⁸ units/mg.
Reconstitution Instructions Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues


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Andrianjafiniony, T. et al. Oxidative Stress, Apoptosis, and Proteolysis in Skeletal Muscle repair after Unloading. Am. J. Physiol. Cell Physiol., 2010; 299: C307-C315.
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