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IL-5, murine recombinant

A cytokine which stimulates B cell growth & eosinophil activation
Catalog #: 4141
SKU-Size Size Price Qty
4141-10 10 μg
$255.00
4141-1000 1 mg
$6,760.00
More Sizes Get Quote

Product Details

Alternate Name Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin 5, IL-5, IL 5, IL-5,
Gene Symbol IL5
Gene ID 16191
Accession # P04401
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 20 mM Sodium phosphate buffer, pH 7.5
Molecular Weight 26.2 kDa
Purity by SDS-PAGE ≥97%
Purity by ≥97%
Endotoxin Level <0.1 ng/μg
Biological Activity Mouse IL-5 is fully biologically active as compared to standard. The ED₅₀, as calculated by the dose-dependent induction of TF-1 cell proliferation, is 1.7ng/ml.
Reconstitution Instructions It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Mouse Interleukin-5 (mIL-5) is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor (IL-5R). Recombinant mIL-5 is produced in E.Coli, comprised of two 113 amino acid chains forming a disulfide-linked homodimer with a molecular weight of 26.2 kDa.


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