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IL-33 Antibody

Polyclonal antibody to detect IL-33 in human samples
Catalog #: 5110
$240.00

Product Details

Cat # +Size 5110-50
Size 50 µg
Antibody Target IL-33
Alternate Name NF-HEV
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen E.coli derived Recombinant Human IL-33
Accession # O95760
Gene ID 90865
Appearance Liquid
Concentration 1 mg/ml
Formulation A sterile filtered antibody solution in PBS, pH 7.2.
Purification Affinity chromatography
Species Reactivity Human
Application Western blot, ELISA, Neutralization, Immunohistochemistry
Positive Control ELISA: Recombinant hIL-33 (Cat # 4193)IHC: Human breast malignant ductal adenocarcinoma
Application & Usage 1) WB: Use 0.1-0.2 µg/ml. The detection limit for recombinant human IL-33 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
2) ELISA: Use 0.5 - 2.0 μg/ml (100 μl/well antibody solution)
3) Neutralization: To yield one-half maxim
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.


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