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IL-21, human recombinant

based on 2 citations in multiple journalsIL-21, human recombinant24.1 4
A cytokine regulating cells of the immune system
Catalog #: 4182
SKU-Size Size Price Qty
4182-10 10 μg
$190.00
4182-50 50 μg
$665.00
4182-1000 1 mg
$4,650.00
More Sizes Get Quote

Product Details

Alternate Name Za11, IL-21, Interleukin-21
Gene Symbol IL21
Gene ID 59067
Accession # Q9HBE4
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized (from 1 mg/ml solution containing no additives).
Molecular Weight 15.5 kDa
Purity by SDS-PAGE ≥90%
Purity by ≥90%
Endotoxin Level <0.1 ng/μg
Biological Activity The recombinant human IL-21 is fully biologically active when compared to standard. The ED₅₀ as determined by the dose-dependent stimulation of human peripheral blood mononuclear cells is <5 ng/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 µg/µl (Note: Gently pippetting to dissolve). The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Recombinant human IL-21 is a homodimeric, non-glycosylated polypeptide containing 133 amino acid residues and has a molecular weight of 15.5 kDa.


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Bolzoni, Marina et al. (2017) IL21R Expressing CD14+CD16+ Monocytes Expand In Multiple Myeloma Patients Leading To Increased Osteoclasts, Haematologica. 2017 Apr;102(4):773-784.
Yoon S-O et al (2009) J. Immunol.; 183: 352-358.
Yoon, S. et al. IL-21 and IL-10 Have Redundant Roles but Differential Capacities at Different Stages of Plasma Cell Generation from Human Germinal Center B Cells. J. Leukoc. Biol. 2009; 86: 1311-1318.
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