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IL-18 Antibody

based on 4 citations in multiple journalsIL-18 Antibody44.1 4
Catalog #: 5179
SKU-Size Size Price Qty
5179-30T 30 µg
$89.00
5179-100 100 µg
$255.00
More Sizes Get Quote

Product Details

Antibody Target IL-18
Alternate Name IL-18, IL18, IL 18, IL-18 Polyclonal Antibody, Anti-IL-18 antibody, IL-18 antibody, Anti-IL-18, Interleukin-18, interleukins
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 41 of human IL-18
Accession # AAC27787
Gene ID 3606
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 30 µg (0.5 mg/ml) affinity purified rabbit anti-human IL-18 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human IL-18 can be used as a positive control (Cat.# 4179-25).
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Interleukin-18 (IL-18), an 18 kDa cytokine, is a single, non-glycosylated polypeptide chain containing 157 amino acids. IL-18 was previously known as interferon-g inducing factor (IGIF). This pleiotropic cytokine is produced by monocyte/macrophage cells. Like IL-12, IL-18 plays an important role in cell-mediated immune responses.


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Zhirong Zhang et al., Gene Deletion of Gabarap Enhances Nlrp3 Inflammasome-Dependent Inflammatory Responses. J. Immunol., Apr 2013; 190: 3517 - 3524.
Zhirong Zhang et al., Gene Deletion of Gabarap Enhances Nlrp3 Inflammasome-Dependent Inflammatory Responses. J. Immunol., Apr 2013; 190: 3517 - 3524.
Nour AM et al (2009) Infect. Immun.; 10.1128/IAI.01032-08.
Squire RC et al. (2007) J. Biol. Chem. 282: 34260 - 34267
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