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IL-13, rat recombinant

A mediator of allergic inflammation and disease
Catalog #: 4166
SKU-Size Size Price Qty
4166-10 10 μg
$180.00
4166-1000 1 mg
$5,200.00
More Sizes Get Quote

Product Details

Alternate Name NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.
Gene Symbol IL13
Gene ID 116553
Accession # P42203
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 12.7 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.


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