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IL-10 Antibody

Polyclonal Antibody to detect IL-10 in human, mouse and rat samples
Catalog #: 6638
SKU-Size Size Price Qty
6638-30T 30 µg
$89.00
6638-100 100 μg
$275.00
More Sizes Get Quote

Product Details

Antibody Target IL-10
Alternate Name CSIF, IL-10, IL10A, TGIF, B-TCGF, GVHDS, MGC126450, MGC126451, RP11-262N9.1, Interleukin-10
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant human protein
Accession # P22301
Gene ID 3586
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 0.5 mg/ml affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity Purified Antibody
Species Reactivity Human, mouse, rat
Application Western blot
Positive Control Western Blot: Jurkat cell lysate
Application & Usage Western blot: 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 20.5 kDa protein containing 161-178 amino acid residues. IL10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.


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