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Product Details
| Alternate Name | Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) |
|---|---|
| Gene Symbol | IL1A |
| Gene ID | 16175 |
| Accession # | Q3U0Y6 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized after extensive dialysis against PBS |
| Molecular Weight | 18.0 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells was found to be < 0.01ng/ml, corresponding to a specific activity of 1 x 108 IU/mg. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of not less than 100 µg/ml. which can then be diluted into other aqueous solutions. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Recombinant mouse Interleukin-1 alpha (IL-1α) produced in E. coli is a non-glycosylated polypeptide chain containing 156 amino acids and has a molecular weight of 18 kDa. Murine IL-1α is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses.
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