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A potent lysosomotropic autophagy inhibitor
Catalog #: B2378
SKU-Size Size Price Qty
B2378-1 1 mg
B2378-5 5 mg
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Product Details

Alternate Name N2-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-N4-(4-fluorophenyl)-6-morpholino-1,3,5-triazine-2,4-diamine, IITZ01
Appearance Crystalline solid
CAS # 1807988-47-1
Molecular Formula C₂₆H₂₃FN₈O
Molecular Weight 482.51
Purity ≥98% by HPLC
Solubility >50 mg/ml in DMSO
InChi InChI=1S/C26H23FN8O/c27-18-7-11-20(12-8-18)29-25-32-24(33-26(34-25)35-13-15-36-16-14-35)28-19-9-5-17(6-10-19)23-30-21-3-1-2-4-22(21)31-23/h1-12H,13-16H2,(H,30,31)(H2,28,29,32,33,34)
PubChem CID 134817273
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


IITZ-01 is a potent potent lysosomotropic autophagy inhibitor; displays >10-fold potent autophagy inhibition than Chloroquine (Cat. No.1825); enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.

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