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IGF-II, Human Recombinant

based on 1 citations in multiple journalsIGF-II, Human Recombinant 14.1 4
A growth promoting hormone during gestation
Catalog #: 4122
SKU-Size Size Price Qty
4122-10 10 μg
$80.00
4122-50 50 μg
$190.00
4122-1000 1 mg
$1,400.00
More Sizes Get Quote

Product Details

Alternate Name Insulin-like Growth Factor-II, Somatamedin A, Insulin-like growth factor II Ala-25 Del, Preptin
Gene Symbol IGF2
Gene ID 3481
Accession # P01344
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives.
Molecular Weight 7.9 kDa (amino acids 25 to 91, with GSHM at N-terminus from His-tag removal)
Purity by SDS-PAGE ≥98%
Endotoxin Level <0.1 ng/μg
Reconstitution Instructions Reconstitute in 10 mM acetic acid to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and or stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

IGF-II (Insulin-like Growth Factor-II) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types. IGF-II is similar to insulin by structure and function, but has a higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, and signals through the tyrosine kinase type I receptor IGF-1R as well as the IGF-II/Mannose-6-phosphate receptor.


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Wang et al,The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis. Mol. Cancer Ther., Apr 2015; 14: 982 - 993.
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