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Ifosfamide

A nitrogen mustard alkylating agent

WARNING: This product can expose you to chemicals including Ifosfamide, which is [are] known to the State of California to cause birth defects or other reproductive harm.  For more information go to  www.P65Warnings.ca.gov.
Catalog #: B2653
SKU-Size Size Price Qty
B2653-10 10 mg
$65.00
B2653-50 50 mg
$260.00
More Sizes Get Quote

Product Details

Alternate Name Isophosphamide; N,3-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; NSC-109724
Appearance Crystalline solid
CAS # 3778-73-2
Molecular Formula C₇H₁₅Cl₂N₂O₂P
Molecular Weight 261.08
Purity ≥98%
Solubility >30 mg/ml DMSO
SMILES C1CN(P(=O)(OC1)NCCCl)CCCl
InChi InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
InChi Key HOMGKSMUEGBAAB-UHFFFAOYSA-N
PubChem CID 3690
MDL Number MFCD00057374
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent. Like cyclophosphamide, ifosfamide serves as a prodrug that is either metabolized to its active DNA alkylating form, isophosphoramide mustard, or catabolized through a dechloroethylation pathway to the neurotoxic and nephrotoxic chloroacetaldehyde.


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