Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

IFN-gamma, murine recombinant

based on 1 citations in multiple journalsIFN-gamma, murine recombinant14.1 4
A critical cytokine for innate and adaptive immunity
Catalog #: 4117
SKU-Size Size Price Qty
4117-20 20 μg
$110.00
4117-100 100 μg
$260.00
4117-1000 1 mg
$1,505.00
More Sizes Get Quote

Product Details

Alternate Name Immune Interferon-γ, type II interferon, T cell interferon, MAF
Gene Symbol IFNG
Gene ID 15978
Accession # P01580
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 10 mM Na2PO4, pH 7.0 + 25 mM NaCl
Molecular Weight 15.6 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by a cytopathic affect inhibition assay with murine NIH 3T3 cells challenged with VSV virus is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 10⁷ units/mg.
Reconstitution Instructions Reconstitute in ddH₂O to a concentration of 1 mg/ml. Further dilutions should be made into RPMI + 10% FCS and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Kajiwara et al., A Critical Role for Human Caspase-4 in Endotoxin Sensitivity. J. Immunol., Jul 2014; 193: 335 - 343.
For more citations of this product click here