IFN gamma Antibody

Catalog #: 5117 | abID:

Product Details

Cat # +Size 5117-100
Size 100 µg
Antibody Target IFNg
Alternate Name Interferon gamma, IFNg, IFN-gamma, IFN gamma
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen E. coli expressed murine IFN-gamma
Accession # NP_032363
Gene ID 15978
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-murine IFN-gamma polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Mouse
Application Western blot, Neutralization, ELISA
Application & Usage Western blot analysis (0.5-1 µg/ml) and neutralization (0.2-1 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.


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