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IFITM3 Antibody

Inhibits entry of viruses into host cells
Catalog #: A2306
SKU-Size Size Price Qty
A2306-50 50 µg
$265.00
A2306-100 100 µg
$425.00
More Sizes Get Quote

Product Details

Antibody Target Human IFITM3
Alternate Name Interferon induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon inducible protein 1-8U; 1-8U; IP15
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human IFITM3
Accession # Q01628
Gene ID 10410
Appearance Liquid
Formulation In PBS with 0.09% (W/V) sodium azide
Purification Protein A, affinity purification
Species Reactivity Human, Mouse
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Interferon induced transmembrane protein 3 (IFITM3) is an antiviral protein which inhibits viral entry into host cells. IFITM3 disrupts intracellular cholesterol homeostatis, which may lead to inactivated newly enveloped viruses which bud from infected cells with a cholesterol depleted membrane. IFITM3 is active against many viruses, including influenza A, Ebola, Dengue, West Nile, HIV-1, and SARS-CoV. While known to restrict infection by SARS-CoV-2, certain mutations of residues within IFITM3 may convert the protein into an enhancer of infection, making this protein an intriguing marker for COVID-19 research.


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