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IDO1 Inhibitor I

A potent indoleamine 2,3-dioxygenase (IDO1) inhibitor
Catalog #: 2745
SKU-Size Size Price Qty
2745-5 5 mg
$95.00
2745-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Appearance White solid
CAS # 914471-09-3
Molecular Formula C₉H₇ClFN₅O₂
Molecular Weight 271.63
Purity ≥98% by HPLC
Solubility DMSO (>25 mg/ml)
SMILES C1=CC(=C(C=C1NC(=C2C(=NON2)N)N=O)Cl)F
InChi InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,13,15H,(H2,12,16)
InChi Key MUVQOOPKPBEAJZ-UHFFFAOYSA-N
PubChem CID 53434622
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

IDO1 Inhibitor I is a potent IDO1 inhibitor that displays IC₅₀ values of 67 and 19 nM for human IDO in enzymatic activity and HeLa cell assays, respectively. It is inactive against tryptophan 2,3-dioxygenase (IC₅₀ > 10 µM).


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