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Icariin

A human phosphodiesterase 5 (PDE5) inhibitor
Catalog #: B2261
SKU-Size Size Price Qty
B2261-10 10 mg
$65.00
B2261-50 50 mg
$175.00
More Sizes Get Quote

Product Details

Alternate Name 4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside
Appearance Light yellow to yellow solid
CAS # 489-32-7
Molecular Formula C₃₃H₄₀O₁₅
Molecular Weight 676.66
Purity ≥95% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES CC1C(C(C(C(O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)OC4C(C(C(C(O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
InChi InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChi Key TZJALUIVHRYQQB-XLRXWWTNSA-N
PubChem CID 5318997
MDL Number MFCD00210516
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Icariin is the active component of the Chinese medicinal plant E. brevicornum that acts as an inhibitor of human phosphodiesterase 5 (PDE5) (IC₅₀ = 5.9 μM). Icariin also promotes the growth and proliferation of neural stem cells from rat hippocampus in a dose-dependent manner.


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