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Iberin

A natural isothiocyanate from cruciferous plants
Catalog #: B2827
SKU-Size Size Price Qty
B2827-1 1 mg
$55.00
B2827-5 5 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name 1-isothiocyanato-3-methylsulfinylpropane, IMSP, NSC 321801
Formulation Solution in ethanol
CAS # 505-44-2
Molecular Formula C₅H₉NOS₂
Molecular Weight 163.26
Purity ≥95%
SMILES CS(=O)CCCN=C=S
InChi InChI=1S/C5H9NOS2/c1-9(7)4-2-3-6-5-8/h2-4H2,1H3
InChi Key LELAOEBVZLPXAZ-UHFFFAOYSA-N
PubChem CID 10455
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -80ºC
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not For Use in Humans.

Details

Iberin is a natural isothiocyanate from cruciferous plants. It is a hydrolysis product of glucosinolate. It induces the expression of phase II detoxification enzymes, quinone reductase (QR) and glutathione S-transferase (GST). It activates Nrf2 regulated antioxidant/detoxifying genes. It induces cell cycle arrest with an inhibition of expression of Cdk2, Cdk4, and Cdk6 proteins and apoptosis with the activation of caspase-9, caspase-3, and PARP in neuroblastoma cells. It is a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa.


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