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A potent, and selective small molecule inhibitor of BET proteins
Catalog #: B1569

In stock

SKU-Size Size Price Qty
B1569-5 5 mg
B1569-25 25 mg

Product Details

Alternate Name 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-1,2,3,4-tetrahydro-2-methyl-6-quinolinyl]-benzoic acid; GSK1324726A
Appearance Crystalline solid
CAS # 1300031-52-0
Molecular Formula C₂₅H₂₃ClN₂O₃
Molecular Weight 435
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C25H23ClN2O3/c1-15-13-23(27-21-10-8-20(26)9-11-21)22-14-19(7-12-24(22)28(15)16(2)29)17-3-5-18(6-4-17)25(30)31/h3-12,14-15,23,27H,13H2,1-2H3,(H,30,31)/t15-,23+/m0/s1
PubChem CID 52912222
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


I-BET276 is a potent, and selective small molecule inhibitor of BET proteins with high affinity to BRD2 (IC₅₀ = 41 nM), BRD3 (IC₅₀ = 31 nM), and BRD4 (IC₅₀ = 22 nM).

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