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Product Details
| Alternate Name | 5-(1, 4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride; HA-1100 hydrochloride |
|---|---|
| Appearance | White solid |
| CAS # | 155558-32-0 |
| Molecular Formula | C₁₄H₁₈ClN₃O₃S |
| Molecular Weight | 343.83 |
| Purity | ≥98% by HPLC |
| Solubility | H₂O (>5 mg/ml) |
| SMILES | C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl |
| InChi | InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H |
| InChi Key | XWWFOUVDVJGNNG-UHFFFAOYSA-N |
| PubChem CID | 11371328 |
| MDL Number | MFCD06411567 |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.
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