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Hydroxychloroquine sulfate

An autophagy inhibitor
Catalog #: B2051
SKU-Size Size Price Qty
B2051-50 50 mg
$65.00
B2051-250 250 mg
$175.00
More Sizes Get Quote

Product Details

Alternate Name 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate; HCQ
Appearance White to off-white solid
CAS # 747-36-4
Molecular Formula C₁₈H₂₆ClN₃O • H₂SO₄
Molecular Weight 434
Purity ≥98% by HPLC
Solubility H2O (>20 mg/ml)
SMILES CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O
InChi InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChi Key JCBIVZZPXRZKTI-UHFFFAOYSA-N
PubChem CID 12947
MDL Number MFCD00078203
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Hydroxychloroquine is a synthetic quinine derivative commonly used as an antimalarial drug. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. It inhibits autophagy and induces autophagic cell death (IC₅₀ = 30 µM), suggesting potential applications in research and medicine.


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