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Hydroxy Dynasore

A dynamin inhibitor
Catalog #: B2642
SKU-Size Size Price Qty
B2642-5 5 mg
$85.00
B2642-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name Dyngo 4a, 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
Appearance Yellow solid
CAS # 1256493-34-1
Molecular Formula C₁₈H₁₄N₂O₅
Molecular Weight 338.31
Purity ≥98% by HPLC
Solubility >30 mg/ml DMSO
SMILES C1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3O)O)O)O
InChi InChI=1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
InChi Key UAXHPUSKEWEOAP-DJKKODMXSA-N
PubChem CID 136227923
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Hydroxy Dynasore is an analog of Dynasore (Cat. No. 1900) that acts as a potent dynamin inhibitor (IC₅₀ values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons.


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