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Human Thyroglobulin

Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).
Catalog #: P1025
SKU-Size Size Price Qty
P1025-20 20 μg
$295.00
P1025-100 100 µg
$450.00
More Sizes Get Quote

Product Details

Alternate Name Thyroglobulin, TGN, AITD3, TG
Gene Symbol TG
Gene ID  7038
Accession # P01266
Appearance Liquid
Molecular Weight 331 kDa
Purity by SDS-PAGE > 95%
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is produced by the thyroid epithelial cells (thyrocytes) which form spherical follicles. Thyroglobulin is subsequently secreted and stored in the follicular lumen.


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