Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Human Thioredoxin 1 (Trx1) Inhibitor Screening Kit (Fluorometric)

Simplest High-Throughput Assay To Screen Thioredoxin 1 Inhibitors
Catalog #: K535

In stock


Product Details

Cat # +Size K535-100
Size 100 assays
Kit Summary • Detection method-Fluorescence (Ex/Em: 490/525 nm)
• Applications- Screening/studying/characterizing Thioredoxin 1 inhibitors
Detection Method Fluorescence (Ex/Em: 490/525 nm)
Species Reactivity Human
Applications Screening/studying/characterizing Thioredoxin 1 inhibitors
Features & Benefits • Rapid, simple & sensitive
• Convenient & HTS
• Includes inhibitor control
Kit Components • Trx1 Assay Buffer
• Trx1 Substrate (Lyophilized)
• DTT (1 M)
• Trx1 Enzyme (Lyophilized)
• Trx1 Inhibitor (50X)
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The human Thioredoxin 1 (Trx1) is a key enzyme that protects cells from oxidative stress by reducing disulfides and methionine sulfoxide groups in oxidized proteins. It also regulates DNA repair and apoptosis. In mammals, Trx1 is necessary for growth and development. However, an aberrant elevated expression of Trx1 is known to promote lung, cervical, pancreatic, colorectal, and breast cancers. In BioVision’s Trx1 Inhibitor Screening Kit, Trx1 reduces quenched di-FITC-labeled oxidized glutathione (Trx1 substrate), to mono-FITC-labeled unquenched reduced glutathione. In the presence of a Trx1 inhibitor (control inhibitor included), the reaction is impeded resulting in lower or no signal. The assay is high-throughput adaptable and can be completed in less than 1 hr.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Subscribe to our Newsletter!!
and automatically get enrolled into a raffle to win Google Home.
Offer valid for US customers only.