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Human recombinant UBE2L3

Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.
Catalog #: 6431
$290.00

Product Details

Cat # +Size 6431-3
Size 3 nmol
Alternate Name Ubiquitin-conjugating enzyme E2 L3, EC 6.3.2.19, Ubiquitin-protein ligase L3, Ubiquitin carrier protein L3, UbcH7, E2-F1, L-UBC, UbcM4.
Gene Symbol UBE2L3
Gene ID 7332
Accession # P68036
Appearance Liquid
Physical Form Description 75 µL of a 40 µM solution (3 nmoles) in 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Molecular Weight 17.861 kDa
Purity by SDS-PAGE ≥95%
Biological Activity Typical enzyme concentration of 100 nM - 1 mM is used for in vitro conjugation, depending on conditions.
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

UBE2L3 (UbcH7) is an E2 (ubiquitin conjugating enzyme) ligase involved in the conjugation of ubiquitin to target substrates, along with E1 and E3 enzymes. UbcH7 has been shown to work with HECT domain E3’s (E6-AP), in addition to RING containing E3’s. UbcH7 is homologous to the UbcH5 family.


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