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Product Details
| Cat # +Size | 6431-3 |
|---|---|
| Size | 3 nmol |
| Alternate Name | Ubiquitin-conjugating enzyme E2 L3, EC 6.3.2.19, Ubiquitin-protein ligase L3, Ubiquitin carrier protein L3, UbcH7, E2-F1, L-UBC, UbcM4. |
| Gene Symbol | UBE2L3 |
| Gene ID | 7332 |
| Accession # | P68036 |
| Appearance | Liquid |
| Physical Form Description | 75 µL of a 40 µM solution (3 nmoles) in 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol. |
| Molecular Weight | 17.861 kDa |
| Purity by SDS-PAGE | ≥95% |
| Biological Activity | Typical enzyme concentration of 100 nM - 1 mM is used for in vitro conjugation, depending on conditions. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not to be used in humans |
Details
UBE2L3 (UbcH7) is an E2 (ubiquitin conjugating enzyme) ligase involved in the conjugation of ubiquitin to target substrates, along with E1 and E3 enzymes. UbcH7 has been shown to work with HECT domain E3’s (E6-AP), in addition to RING containing E3’s. UbcH7 is homologous to the UbcH5 family.
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