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Human recombinant UBE2E2 (UbcH8)

Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.
Catalog #: 6438
$315.00

Product Details

Cat # +Size 6438-3
Size 3 nmol
Alternate Name RIG-B, UBCH8, MGC40331, UBE2L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrier protein L6, and Retinoic acid-induced gene B protein.
Gene Symbol UBE2E2
Gene ID 7325
Accession # Q96LR5
Appearance Liquid
Physical Form Description 75 µL of a 40 µM solution (3 nmoles) in 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Molecular Weight 22.255 kDa
Purity by SDS-PAGE ≥95%
Biological Activity Protein concentration of 100 nM - 1 µM is recommended for in vitro conjugation.
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Ubiquitin-conjugating enzyme E2 (UBE2E2) is a protein that in humans is encoded by the UBE2E2 gene. Amino acid sequence within the UBC domain of UBE2E2 shares over 90% identity with human UbcH6, mouse UbcM2, and Drosophila UbcD2, whereas the N-terminal region shows little amino acid sequence similarity with known proteins. The UBE2E2 protein forms a thioester bond with ubiquitin in an E1-dependent manner and mediates the transfer of ubiquitin from a ubiquitin-activating enzyme (E1) to a substrate protein or E3 ligase.


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