Human Recombinant PPP1CA

Crucial for cell division
Catalog #: 6370 | abID: ab113150

Product Details

abID ab113150
Cat # +Size 6370-10
Size 10 μg
Alternate Name Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PP1alpha, PPP1A.
Gene Symbol PPP1CA
Gene ID 5499
Accession # P62136
Source E. Coli
Appearance Liquid
Physical Form Description 0.25 mg/ml solution in 50 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 1 mM DTT, 0.15 M NaCl, 1 mM MnCl2 and 0.1 mM PMSF.
Molecular Weight 39.7 kDa (350 aa, 1-330 aa + NT His-Tag)
Purity by SDS-PAGE ≥80%
Biological Activity Specific activity: >3,000 units/mg.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSDSEKLNLD SIIGRLLEVQ GSRPGKNVQL TENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KD
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Serine/Threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) is crucial for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The PPP1CA protein may have a significant role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.


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